Cellular Signaling Patterns Drive Gene Expression Through mRNA Stability Mechanisms
Scientists have uncovered how different patterns of JNK signaling activation translate into distinct gene expression profiles. The research demonstrates that mRNA stability plays a crucial role in determining how cells interpret dynamic signaling information over time, according to recent findings published in npj Systems Biology and Applications.
Signaling Dynamics Reveal Complex Cellular Communication
New research indicates that cells use sophisticated timing mechanisms to interpret environmental signals, with recent findings suggesting that the dynamics of JNK activation play a crucial role in determining gene expression outcomes. According to reports published in npj Systems Biology and Applications, the pattern of JNK signaling—whether sustained, transient, or pulsed—directly influences which genes are activated and for how long.